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YCR annual science meeting
YCR Annual Science Meeting 2005
University of Leeds
Tuesday 28 June
Programme
Please note that to attend this event you must have registered in advance by the closing date. You cannot register on the day.
| 8.45am |
Registration and Coffee
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| 9.30am |
Welcome
Professor E A Dawes
(Chairman, Scientific Advisory Committee)
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| 9.35am |
Open Papers - Scientific Session 1
|
| 10.35am |
Coffee, Poster Session and Scientific Exhibition
|
| 11.05am |
The Douglas Shortridge Memorial Lecture Professor Harald zur Hausen (German Cancer Research Centre, Heidelberg, Germany)
|
| 12.05pm |
Buffet Lunch and Scientific Exhibition
|
| 1pm |
Poster viewing
|
| 2pm |
Open Papers - Scientific Session 2
|
| 3.15pm |
Tea, Poster Session & Scientific Exhibition
|
| 3.45pm |
Open Papers - Scientific Session 3
|
| 4.45pm |
Announcement of Poster Award
|
| 4.50pm |
Closing address
Professor E A Dawes
(Chairman, Scientific Advisory Committee) |
Scientific presentations to be 15 minutes duration and the Guest Lecture is 1 hour including questions.
The Open Papers and Guest Lecture will be held in the
Rupert Beckett Lecture Theatre, Michael Sadler Building.
The Poster presentations, Refreshments and Scientific Exhibition will be held Rooms LG15 & LG19 in the Michael Sadler Building (adjacent to the Lecture Theatre).
Please stand by your Posters from 1pm to 2pm and remove them from the stands at the end of the afternoon Poster Session.
Organising Committee:
Professor E A Dawes
Dr G E Blair
Professor J Milner
Professor M Seymour
Professor P Quirke
This meeting was sponsored by:
Ambion Europe Ltd
BD Biosciences
Bioline Ltd
Caltag-Medsystems
Camlab Limited
Genetic Research Instrumentation
Merck Bioscience Ltd
Miltenyi Biotec Ltd
Perbio Sciences UK Ltd
Qiagen Ltd
Thermo Electron Corporation
Thistle Scientific Ltd
Web Scientific Ltd
Yorkshire Bioscience Ltd
|
OPEN PAPERS - SCIENTIFIC SESSION 1
Chair: Professor P Quirke
|
9.35am
|
CSMD1 AN ADHESION PROTEIN WITH REDUCED EXPRESSION IN HUMAN BREAST CANCER
Dr S M Bell, Dr C Toomes & Dr A P Jackson
Molecular Medicine Unit, St James's University Hospital, Leeds LS9 7TF
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| 9.50am |
ESTROGEN RECEPTORb VARIANTS IN TAMOXIFEN-RESISTANT BREAST CANCER
Valerie Speirs1, Daniel J Scott1 and Indra Poola21Academic Unit of Molecular Medicine, University of Leeds, Leeds LS9 7TF
2Howard University, Washington DC, USA
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| 10.05am |
DEFINING POTENTIAL TARGETS FOR CELL BASED IMMUNOTHERAPY OF COLORECTAL CANCER
S E Perry1, G P Cook2, P Quirke3, A Melcher4, C Verbeke5 & G E Blair1
1Molecular Cell Biology Research Group, Faculty of Biological Sciences, &3Department of Pathology, University of Leeds LS2 9JT
2Unit of Molecular Medicine,4CRUK &5Histopathology, St James's University Hospital, Leeds LS9 7TF
|
| 10.20am |
USE OF HYPOXIA-RESPONSIVE BACTERIAL PROMOTER ELEMENTS IN SALMONELLA TO TARGET GENE THERAPY TO HYPOXIC REGIONS OF SOLID TUMOURS
Rachel M Ryan1,2, Jeffrey Green2, Siobhan C Kehoe3, Judith H Harmey3 and Claire E Lewis1
Tumour Targeting Group1 and Molecular Biology and Biotechnology Department2, University of Sheffield and Department of Surgery, Royal College of Surgeons in Ireland, Dublin3
Open Papers 1
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| 10.35am |
COFFEE, POSTER SESSION AND SCIENTIFIC EXHIBITION
|
| 11.05am |
The Douglas Shortridge Memorial Lecture
CANCER INDUCTION BY INFECTIONS - MODES AND MECHANISMS
Professor Harald zur Hausen, German Cancer Centre, Heidelberg.
Introduced by Professor E A Dawes
|
12.05pm
1pm |
BUFFET LUNCH AND SCIENTIFIC EXHIBITION
POSTER VIEWING
Posters
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OPEN PAPERS - SCIENTIFIC SESSION 2
Chair: Professor M T Seymour
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| 2pm |
ALIPHATIC AMINE N-OXIDES AS PRODRUG TOPOISOMERASE II INHIBITORS: DEVELOPMENT OF AQ4N (BANOXANTRONE)
Patterson L H
The Institute of Cancer Therapeutics, University of Bradford, Bradford BD7 1DP
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| 2.15pm |
MULTI LAYERED PERCEPTRON NETWORKS APPLIED FOR BREAST LESION CLASSIFICATION
Sreenivas M, Gibbs P, Turnbull LW
Centre for Magnetic Resonance Investigations, University of Hull
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| 2.30pm |
DIFFUSION WEIGHTED IMAGING OF NORMAL AND PATHOLOGICAL PROSTATE TISSUE AT 3.0T
M D Pickles, P Gibbs, M Sreenivas & L W Turnbull
Centre for Magnetic Resonance Investigations, University of Hull
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| 2.45pm |
UPREGULATION OF PRO-ANGIOGENIC INTERLEUKIN-8 BY HYPOXIA AND NUTRIENT DEPRIVATION IN LUNG CANCER CELLS
YM Zhu1, X Xue1, SSH Chan1, N M Tempest1, C E Millward1, C E Lewis2, P J Woll1
1Cancer Studies and Clinical Oncology,2Tumour Targeting group, University of Sheffield
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| 3pm |
FACTORS INFLUENCING THE OUTCOME OF TREATMENT OF METASTATIC COLORECTAL CANCER: GENETIC POLYMORPHISMS AND DOSE INTENSITY
Maria Marples1, Angela Cox2, Dan Connley2, Vanessa Spawton2, Helen Cramp2, Lynne Calkwell3 and Anthony Maraveyas3
1Cancer Research Centre, Weston Park Hospital, Sheffield,2Institute for Cancer Studies, Sheffield Medical School, and3Princess Royal Hospital, Hull
Open Papers 2
|
| 3.15pm |
TEA, POSTER SESSION AND SCIENTIFIC EXHIBITION
|
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OPEN PAPERS - SCIENTIFIC SESSION 3
Chair: Professor J Milner
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| 3.45pm |
BPV INITIATOR PROTEIN RECRUITMENT BY TRANSCRIPTION FACTOR E2 IS CONTROLLED BY A REDOX SENSITIVE INTERNAL DIMERISATION INTERFACE
Cyril M Sanders1, Dmytro Sizov2, David Burgin1, Miguel Ortiz-Lombardia2 and Alfred Anston2.
1Institute for Cancer Studies, University of Sheffield
2York Structural Biology Laboratory, University of York
|
| 4pm |
MUTATION OF THE N-TERMINAL DIMERISATION INTERFACE OF HUMAN PAPILLOMAVIRUS E2 PROTEIN
Elena E. Hernandez-Ramon, Claire Burn, Wenke Zhang*,Julie E. Burns, Stephanie Allen* and Norman J. Maitland
YCR Cancer Research Unit, Department of Biology, University of York, York YO10 5DD
*School of Pharmaceutical Sciences, University of Nottingham, Nottingham NG7 2RD
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| 4.15pm |
SPECIFIC KNOCKING DOWN E7 EXPRESSION IN HPV-16 POSITIVE CARCINOMA CELL LINE INDUCES APOPTOSIS
Ming Jiang and Jo Milner
Yorkshire Cancer Research P53 Group, Department of Biology, University of York, York YO10 5DD
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| 4.30pm |
CIZ1 PROMOTES INITIATION OF MAMMALIAN DNA REPLICATION
Dawn Coverley1, Jackie Marr2 and Justin Ainscough3
1Department of Biology (Area 5), University of York YO10 5YW
2Hutchinson/MRC Research Centre, MRC Cancer Cell Unit, Hills Road, Cambridge CB2 2XZ
3Institute for Cardiovascular Research, Leeds University LS2 9JT
Open Papers 3
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| 4.45pm |
ANNOUNCEMENT OF POSTER AWARD
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| 4.50pm |
CLOSING ADDRESS
Professor E A Dawes |
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