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YCR annual science meeting

YCR Annual Science Meeting 2007

Tuesday 04 September 2007
Clarendon Lecture Theatre
and
Medical School Foyer
University of Leeds
Programme

Please note that to attend this event you must have registered in advance by the closing date. You cannot register on the day.

8.45am Registration and Coffee
9.30am Welcome
Professor R Cartwright
(Chairman, Scientific Advisory Committee)
9.35am Open Papers - Scientific Session 1
10.35am Coffee, Poster Session and Scientific Exhibition
11.05am

Open Papers - Scientific Session 2

12.05pm Buffet Lunch and Scientific Exhibition
1pm Poster viewing
2pm Open Papers - Scientific Session 3
Special Lecture - Professor Nicol Keith
"Developing and Delivering Novel Cancer Therapeutics"
3.15pm Tea, Poster Session & Scientific Exhibition
3.45pm Professor Thomas Lindahl (CRUK London Research Institute Clare Hall Laboratories)
"Repair of endogenous precarcinogenic DNA damage"
4.45pm Announcement of Poster Award
4.50pm Closing address
Professor R Cartwright
(Chairman, Scientific Advisory Committee)


Scientific presentations to be 15 minutes duration and the Guest Lecture is 1 hour including questions.

The Open Papers and Guest Lecture will be held in the
Clarendon Lecture Theatre.

The Poster presentations, refreshmentsand Scientific Exhibition will be held in the Medical School Foyer (adjacent to the Lecture Theatre).

Please stand by your Posters from 1pm to 2pm and remove them from the stands at the end of the afternoon Poster Session.


Organising Committee:
Professor R Cartwright
Dr G E Blair
Professor P Quirke
Professor A J Milner
Professor P Andrews

This meeting was sponsored by:
Applied Biosystems
Barloworld Scientific Ltd
BD Biosciences
Beckman Coulter UK Ltd
Camlab Ltd
Cogenics
Eppendorf UK Ltd
HORIBA ABX
PAA Laboratories Ltd
Qiagen Ltd
Roche Diagnostics Ltd
Thistle Scientific Ltd


OPEN PAPERS - SCIENTIFIC SESSION 1
Chair: Professor P Quirke

9.35am
INVESTIGATION OF CHLOROMETHYLINDOLINES AS TUMOUR-SELECTIVE AGENTS
Klaus Pors, Steve D Shnyder, Mark Sutherland, Paul Loadman, Jon Laye, Stephanie Guest, Nicola Harris, Patricia Cooper, Mark Searcey* and
L H Patterson.
Institute of Cancer Therapeutics, University of Bradford, West Yorkshire BD7 1DP
*School of Chemical Sciences and Pharmacy, University of East Anglia, Norwich, Norfolk NR4 7TJ.
9.50am MRI-GEL DOSIMETRY: STATE-OF-THE-ART RADIOTHERAPY REQUIRES STATE-OF-THE-ART VERIFICATION
Gary P Liney, M Godber, AD Wilson, AW Beavis, JW Goodby and Lindsey W Turnbull
MRI Centre, Hull Royal Infirmary, Anlaby Road, Hull HU3 2JZ.
10.05am THE QUALITY OF SURGERY IN COLONIC CANCER
West Nick P & Quirke Phil
Pathology & Tumour Biology, Leeds Institute of Molecular Medicine
10.20am

INFLUENCE OF TUMOUR CELL DEATH MECHANISMS AND IMMUNOREGULATORY T CELLS ON TUMOUR GROWTH AND IMMUNITY
1,2Sarah L Haywood-Small, 1K Hopkinson, 2MWR Reed, 2N J Brown and 1AG Pockley.
1Immunobiology Research Unit and 2Microcirculation Research Group, School of Medicine and Biomedical Sciences, University of Sheffield, Sheffield S10 2JF.

Open Papers 1


10.35am

COFFEE, POSTER SESSION AND SCIENTIFIC EXHIBITION



OPEN PAPERS - SCIENTIFIC SESSION 2
Chair: Professor A J Milner
11.05am ROLE OF THE POZ DOMAIN IN TRANSCRIPTIONAL REGULATION BY MIZ-1
Mark A Stead, Gareth O Rosbrook, Thomas A Edwards and Stephanie C Wright.
Institute of Molecular and Cellular Biology, University of Leeds, Leeds LS2 9JT

11.20am

EPIGENETIC PRIMING OF THE GM-CSF LOCUS IN MYELOID CELLS AND IN AML BY GATA-1 AND GATA-2.
Fernando Calero-Nieto, Euan Baxter, Brett Johnson, Andrew Bert, and Peter Cockerill.
Experimental Haematology, Leeds Institute of Molecular Medicine, University of Leeds, Wellcome Trust Brenner Building, St James's University Hospital, Leeds LS9 7TF

11.35am REPRESSOSOME FORMATION AND DISRUPTION REGULATES THE KAPOSI'S SARCOMA ASSOCIATED HEPESVIRUS LATENT-LYTIC SWITCH.
Faye Gould and Adrian Whitehouse
Institute of Molecular and Cellular Biology, University of Leeds LS2 9JT
11.50am

INVESTIGATING THE POTENTIAL ROLE OF RECQ5 IN THE REINITIATION OF STALLED REPLICATION FORKS
Rachel Blundred, Thomas Helleday, Alistair Goldman and Helen Bryant
Institute of Cancer Studies, University of Sheffield.

Open Papers 2


12.05pm BUFFET LUNCH AND SCIENTIFIC EXHIBITION
1pm

POSTER VIEWING

Posters


OPEN PAPERS - SCIENTIFIC SESSION 3
Chair: Professor P Andrews

2pm VELOPING AND DELIVERING NOVEL CANCER THERAPEUTICS
Professor Nicol Keith
Centre for Oncology and Applied Pharmacology, University of Glasgow, Cancer Research UK Beatson Labs, Garscube Estate, Glasgow G61 1BD
2.30pm

USE OF GREEN FLUORESCENT PROTEIN (GFP)-IMAGING TO VISULAISE IN VIVO RESPONSES TO THE ANTI-TUMOUR AGENT TRAIL
Neil Cross, Anne Fowles, Srdjan Vitovski, Nickie Jokonya, Ingunn Holen, Freddie Hamdy and Colby Eaton
Academic Urology Unit, University of Sheffield Medical School.

2.45pm RE-TARGETING BACULOVIRUS TO PROSTATE CANCER
Stephanie L Swift, L J Georgopoulous, Julie E Burns and Norman J Maitland
YCR Cancer Research Unit, Department of Biology (Area 13), University of York, Heslington, York YO10 5DD
3pm CROSS-TALK BETWEEN SITE-SPECIFIC MODIFICATIONS ON P53 AND HISTONE H3
Lorna J Warnock, Rachel Adamson, Cain Lynch and Jo Milner
Yorkshire Cancer Research P53 Group, Department of Biology, University of York, York YO10 5DD
3.15pm

TEA, POSTER SESSION AND SCIENTIFIC EXHIBITION

Chair: Professor R Cartwright

3.45pm

REPAIR OF ENDOGENOUS PRECARCINOGENIC DNA DAMAGE
Professor Thomas Lindahl, Principal Scientist, Cancer Research UK London Research Institute Clare Hall Laboratories, South Mimms, Hertfordshire EN6 3LD

Open Papers 3


4.45pm ANNOUNCEMENT OF POSTER AWARD

4.50pm

5pm

CLOSING ADDRESS
Professor R Cartwright

WINE AND CANAPES