Directly or indirectly, cancer will touch everyone's lives. There is no greater or more worthwhile challenge than the ongoing battle to develop and improve anti-cancer treatments, for everyone's sake.
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programme of research
UNIVERSITY OF BRADFORD
2007/8
Institute of Cancer Therapeutics
Director: Professor L.H. Patterson
L. H. Patterson
K. Afarinkia
R. A. Falconer
K. Pors
Design, synthesis and antitumour selectivity of peptide conjugates as metalloproteinase -activated delivery devices
Design, synthesis and pharmacology of unnatural sugars developed as inhibitors of tumour expressed polysialyltransferases
Design and synthesis of Golgi mannosidase II inhibitors
Design and synthesis of Heparanase inhibitors
Design and Synthesis of Chemokine Antagonists
Design, synthesis and biological evaluation of chloromethylindolines as specific substrates for tumour expressed cytochrome P450s.
Design, synthesis and biological evaluation of tumour hypoxia-selective azaheterocyclic-N-oxides
L. H. Patterson
C. W. Sutton
Development of mass spectrometry-based proteomic analysis of cytochromes P450 to aid target validation and drug discovery.
Development of mass spectrometry-based proteomic analysis of tumour and stromal matrix metalloproteinases to aid target validation and drug discovery.
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