research publications

University of Bradford  

2007/08

Institute of Cancer Therapeutics
Director: Prof Laurence H. Patterson    


Steward WP, Middleton M, Benghiat A, Loadman PM, Hayward C, Waller S, Ford S, Halbert G, Patterson LH, Talbot D.
The use of pharmacokinetic and pharmacodynamic end points to determine the dose of AQ4N, a novel hypoxic cell cytotoxin, given with fractionated radiotherapy in  a phase I study.
Ann Oncol. (2007) 18(6):1098-103.  

Atkinson SJ, Loadman PM, Sutton C, Patterson LH, Clench MR.
Examination of the distribution of the bioreductive drug AQ4N and its active metabolite AQ4 in solid tumours by imaging matrix-assisted laser desorption/ionisation mass spectrometry.
Rapid Commun Mass Spectrom. (2007);21(7):1271-6.  

Lane CS, Wang Y, Betts R, Griffiths WJ, Patterson LH.
Comparative cytochrome P450 proteomics in the livers of immunodeficient mice using 18O stable isotope labeling.
Mol Cell Proteomics. 2007;6(6):953-62.  

Afarinkia, K.; Bahar A.; Neuss, J.
Synthesis of Hydrophobically Modified Analogues of Adenophorine
(2007) Synlett, 1375-1378.  

Afarinkia, K.; Ndibwami, A.
A General Synthesis of Phenantridinone Alkaloids
(2007), Synlett, 13940-1944.  

Ribeiro Morais, G.; Falconer, R.A.
Efficient one-pot synthesis of glycosyl disulphides
(2007),  Tetrahedron Lett., 48, 7637-7641.