programme of research

University of Hull

2001/2

Centre for Magnetic Resonance Investigations
Scientific Director: Professor L W Turnbull

L.W. Turnbull
D. Manton
P. Kneeshaw
P. Gibbs
G. Liney
Role of dynamic MR imaging in the investigation of de novo architectural distortion, equivocal breast cytology, and sub 1 cm breast lesions.

P. Kneeshaw
M. Lowry
L.W. Turnbull
Determination of role of MRI in classification of disease in patients with indeterminate, mammographically detected micro calcification.

Comparison of extent of DCIS determined by XRM, MRI and histopathology, and correlation with immunohistochemical markers of angiogenesis.

M. Lowry
D. Manton
P. Gibbs
L.W. Turnbull
Determination of early response to neoadjuvant chemotherapy for locally advanced primary breast cancer by dynamic MR imaging and proton spectroscopy.

M. Lowry
D. Manton
L.W. Turnbull
Effect of conventional hormone replacement therapy and a specific oestrogen receptor modulator on breast parenchymal volume and contrast uptake characteristics.

L.W. Turnbull
Determination of the comparative effectiveness of MR imaging in women with primary breast cancer scheduled for wide local excision.

P. Gibbs
L.W. Turnbull
Identification of MR derived parameters providing prognostic information in newly-diagnosed primary prostate cancers.

B. Wang
L.W. Turnbull
Determination of radiotherapy and GnRH analogue induced effects on MR derived parameters of neovascularisation.

P. Gibbs
L.W. Turnbull
Evaluation of tensor, trace and anisotropic diffusion in differentiation of benign and malignant prostatic tumours.

P. Gibbs
P. Kneeshaw
L.W. Turnbull
Role of MR imaging in intensity modulated radiotherapy planning, with particular reference to prostate movement and dose escalation.

G. Liney
Development and clinical applications of novel poly-acrylamide gels in 3D evaluation of inversely planned, intensity modulated radiotherapy dose distributions.

L.W. Turnbull
G. Hall
Determination of diagnostic and staging accuracy of dynamic and conventional MR imaging in suspected ovarian malignancy.

Correlation of MR derived parameters of neovascularisation with immunohistochemical measurement of native somatostatin, somatostatin receptors and other neovascularisation-related factors in primary ovary tumours.

Correlation of current prognostic factors (CA125, FIGO stage) with MR derived and immunohistochemical measurement of parameters of neoangiogenesis.