Directly or indirectly, cancer will touch everyone's lives. There is no greater or more worthwhile challenge than the ongoing battle to develop and improve anti-cancer treatments, for everyone's sake.
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programme of research
University of Hull
2004/5
Academic Department of Radiology
Yorkshire Cancer Research
Professor of Radiology
Professor L.W. Turnbull
M. Lowry
P. Gibbs
G.P. Liney
D. Manton
C. Tan
M. Pickles
M. Sreenivas
L.W. Turnbull
Differentiation of benign from malignant breast lesions using dynamic contrast-enhanced imaging (DCE-MRI), diffusion-weighted imaging, R2*, proton MR spectroscopy and textural analysis. Determination of the role of MR imaging in the management of women with primary breast cancer scheduled for wide local excision. Assessment of the role of DCE-MRI for the management of locally advanced breast cancer and early prediction of possible outcome. Development of automated techniques for analysis of tumour volume. Development of neural networks for automated breast lesion differentiation.
P. Gibbs
M. Pickles
L.W Turnbull
M. Lowry
Development of diffusion-weighted and diffusion tensor imaging at 3T for tissue discrimination and use in treatment monitoring. Use of DCE-MRI with arterial input function at 3T to discriminate between benign and malignant tissue. Development of proton spectroscopy of the prostate at 3T. Role of photo-dynamic therapy in the treatment of prostate malignancy. Use of multiple data inputs in optimising radiotherapy delivery for prostate cancer.
G. Liney
R. Alvarez-Garcia
L.W. Turnbull
Use of DCE-MRI in the management of patients with primary head and neck tumours. Development of multiple MR imaging and spectroscopy techniques to determine the extent of brain tumour to optimise intensity modulated radiotherapy delivery. Development of radio-sensitive gels for quantitation and quality assurance of conventional and intensity modulated radiotherapy delivery.
L.W. Turnbull
Optimisation of conventional and dynamic imaging techniques at 3T and development of MR spectroscopic imaging for differentiating between benign and malignant ovarian tumours. Examination of the role of DCE-MRI and other MR techniques for the prediction of response of inoperable ovarian tumours to neoadjuvant chemotherapy. Use of 3T MR imaging in the staging of cancer of the cervix uteri, endometrium and vagina. Examination of the role of PDT in the treatment of vulval intra-epithelial neoplasia.
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