programme of research

University of Leeds

2003/4

FACULTY OF MEDICINE, DENTISTRY, PSYCHOLOGY AND HEALTH
Dean of the Faculty: Professor E.W. Hillhouse

School of Medicine
Dean of the School: Professor E.W. Hillhouse

Academic Unit of Epidemiology and Health Services Research
Head of Academic Unit: Prof. C.P. Wild


L.J. Hardie
G.W.B. Clark
C.P. Wild
The role of free radical induced DNA damage during the evolution of oesophageal adenocarcinoma


M.N. Routledge
E. Ingham
C.P. Wild
Genotoxic effects of binary carcinogen exposure in DNA and skin cells


D. Forman
M. Scott
C.P. Wild
Identification of Barrett's Oesophagus patients at high risk of progression to oesophageal adenocarcinoma using molecular markers

Academic Unit of General Surgery, Medicine and Anaesthesia
Head of Academic Unit: Prof. P.D. Howdle

D. Burke
J. Uddin
P. Jones
P. Quirke
Tumour vascularity, cellular proliferation and the role of angiopoietins in colorectal cancer

Academic Unit of Molecular Medicine
Head of Academic Unit: Prof. D.T. Bonthron


J.M. Askham
E.E. Morrison
Functional characterisation of human EBI homologues


S.M. Bell
A.P. Jackson
Characterisation of OSC1, a novel tumour suppressor in oral squamous cell carcinoma and other cancers


C. Bonifer
D. Clarke
Expression of oncogenic versions of c-myb and AML1 in in vitro differentiated mouse embryonic stem cells


P.N. Cockerill
Activation of the GM-CSF locus in acute myeloid leukaemia


P.L. Coletta
Dr C. Bonifer
M.A. Hull
Tumour initiation and progression in theApcMin mouse model of familial adenomatous polyposis


J.E. Crabtree
M.F. Dixon
P.A. Robinson
Inhibition of Helicobacter pylori induced epithelial proliferative responses: a novel approach for cancer chemoprevention


V. Speirs
D.J. Scott
Further defining the role of estrogen receptor b in breast cancer: using variant isoforms to predict hormone response

Academic Unit of Oncology and Haematology
Head of Academic Unit: Prof. P.J. Selby

P. Hillmen
A.S. Jack
A.C. Rawstron
M.S. Gilthorpe
A study of the prevalence of occult B-cell lymphoproliferative disorders in the healthy population and in the family members of patients


S.C. Sak
D.T. Bishop
A.E. Kiltie
A molecular genetic analysis of DNA repair and bladder cancer


E.E. Morrison
J.M. Askham
M. Adams
Investigation of the role of TOG in colorectal cancer

Academic Unit of Pathology
Head of Academic Unit: Prof. P. Quirke

P. Quirke
M. Seymour
Selection of patients for adjuvant therapy in colorectal cancer V getting it right with molecular profiling

FACULTY OF BIOLOGICAL SCIENCES
Chair of the Faculty: Professor K.T. Holland

School of Biochemistry and Molecular Biology
Head of the School: Professor A.J. Turner

K. Barnes
E. McIntosh
D. Itchayanan
J. Bentley
S.A. Baldwin
Investigation into the role of Bcr-Abl-induced abnormalities in glucose transport regulation in the pathogenesis of chronic myeloid leukaemia


G.E. Blair
S.C. Wright
A. Whitehouse
E.H. Hewitt
Studies on the expression and intracellular localisation of viral and cellular oncoproteins


G.E. Blair
G. Bottley
J. Jarvis
High risk human papilloma virus oncogenes: studies on antigen processing and presentation in transformed cells, organotypic cultures and cell lines


S.E. Perry
G.E. Blair
G.P. Cook
A.A. Melcher
P. Quirke
Use of post-genomic technologies to discover new targets for colorectal cancer immunotherapy


B.A. Usmani
A.J. Turner
Functional genomics of a proteinase gene family (m13; nep) in human prostate cancer


A. Whitehouse
D. Goodwin
Kaposi's sarcoma: investigating the human herpesvirus-8 latent-lytic switch


S.C. Wright
Identification of genes that are transcriptionally repressed by Mxil


S.C. Wright
Regulation of the Miz-1 transcription factor

YORKSHIRE CANCER RESEARCH PHOTODYNAMIC THERAPY GROUP
Centre for Photobiology and Photodynamic Therapy

A multidisciplinary approach to the development of photodynamic therapy for cancer treatment
(A multidisciplinary group of staff from the School of Biochemistry and Molecular Biology, the School of Biomedical Sciences, the Department of Colour and Polymer Chemistry, the School of Medicine, Cookridge Hospital, Leeds General Infirmary, St James's Hospital and Goole and District Hospital.)

Principal Investigator: Professor S.B. Brown

S.B. Brown
R. Ackroyd
K. Battye
A. Bell
D. Berger
A. Brown
N.J. Brown
M.L. Denti
E. Eagle
A. Foley
S. Gorman
J. Griffiths
A.J. Holroyd
C. Kelty
G.Lane
J. Mama
P. Marks
K. Mellish
K Moghissi
C. O'Grady
J. Petit
M.M. Rashid
M.W.R. Reed
D.J.H. Roberts
F. Roberts
J. Schofield
M.R. Stringer
E. Taylor
R. Tyler
D.I.Vernon
I. Walker
A multidisciplinary approach to the development of photo-dynamic therapy for cancer treatment