programme of research

University of Leeds

2005/6

FACULTY OF MEDICINE AND HEALTH
Dean of the Faculty: Professor E.W. Hillhouse

The Leeds Institute of Molecular Medicine
Director: Professor T.H. Rabbitts

Academic Unit of Oncology & Haematology
Head of Academic Unit: Prof. P.J. Selby


P. Hillmen
A.S. Jack
A.C. Rawstron
M.S. Gilthorpe
A study of the prevalence of Occult B-cell lymphoproliferative disorders in the healthy population and in the family members of patients.

FACULTY OF MEDICINE AND HEALTH
Dean of the Faculty: Professor E.W. Hillhouse

The Leeds Institute of Genetics, Health and Therapeutics (LIGHT)
Acting Director: Professor C.P. Wild

Centre for Epidemiology and Biostatistics
Head of Centre: Professor C.P. Wild

M.N. Routledge
E. Ingham
C.P. Wild
Genotoxic effects of binary exposures of carcinogens on skin cells.

L.J. Hardie
C.P. Wild
Investigation of the risks of genetic damage associated with chromoendoscopy in Barrett's Oesophagus patients.

The Leeds Institute of Molecular Medicine
Director: Professor T.H. Rabbitts

Academic Unit of Molecular Medicine
Director: Professor D.T. Bonthron

J.M. Askham
E.E. Morrison
Functional characterisation of human EB1 homologues.

S.M. Bell
A.P. Jackson
Characterisation of OSC1, a novel tumour suppressor in oral squamous cell carcinoma and other cancers.

S.M. Bell
V. Speirs
MCPH1, a potential predictor for response to cancer chemotherapy.

C. Bonifer
D. Clarke
Expression of oncogenic versions of c-myb and AML1 in in vitro differentiated mouse embryonic stem cells.

P.N. Cockerill
Epigenetic priming of the GM-CSF locus in acute myeloid leukaemia.

J.E. Crabtree
M.F. Dixon
P.A. Robinson
Inhibition of Helicobacter pylori induced epithelial proliferative responses: a novel approach for cancer chemoprevention.

J.E. Crabtree
D.A. Brooke
P.L. Coletta
P.A. Robinson
A novel transgenic model for analysis of Helicobacter pylori induced gastric carcinogenesis.

E.A. de Wynter
G.P. Cook
Towards a better definition of the human haemopoietic stem cell; surface marker expression and functional activity.

J.E. Linley
M. Hunter
G.I. Sandle
Potassium channels as biomarkers of carcinogenesis in human colon.

V. Speirs
M. Cummings
Functional significance of altered prostaglandin-signalling in hormone resistant breast cancer.

Academic Unit of Oncology & Haematology
Head of Academic Unit: Prof. P.J. Selby

A.E. Kiltie
D.T. Bishop
Molecular epidemiology of DNA repair and bladder cancer.

A.E. Kiltie
J. Bentley
M.A. Knowles
The influence of DNA double strand break signalling proteins on outcomes following radiotherapy for bladder cancer.

FACULTY OF BIOLOGICAL SCIENCES
Dean of the Faculty: Professor A.J. Turner

G.E. Blair
G.P. Cook
G. Bottley
Assessing the role of human papillomavirus (HPV) oncoproteins in regulating cell-mediated immunity: implications for cervical cancer.

P. Robinson
S.E. Perry
G.E. Blair
G.P. Cook
A.A. Melcher
P. Quirke
Use of post-genomic technologies to discover new targets for colorectal cancer immunotherapy.

A. Whitehouse
Cellular proteins which regulate the latent-lytic switch in Kaposi's sarcoma associated herpesvirus.

S.C. Wright
Regulation of the Miz-1 transcription factor.

S.C. Wright
Transcriptional targets of mammalian Mad family proteins.

B.A. Usmani
A.J. Taylor
Expression profiling of the NEP family of metalloproteinases in prostate cancer.