RESEARCH

Directly or indirectly, cancer will touch everyone's lives. There is no greater or more worthwhile challenge than the ongoing battle to develop and improve anti-cancer treatments, for everyone's sake.

programme of research


University of Leeds

2006/7


FACULTY OF MEDICINE AND HEALTH
Dean of the Faculty: Professor E.W. Hillhouse

The Leeds Institute of Genetics, Health and Therapeutics (LIGHT)
Director: Professor C.P. Wild



L.J. Hardie
C.P. Wild
Investigation of the risks of genetic damage associated with chromoendoscopy in Barretts Oesophagus patients.


The Leeds Institute of Molecular Medicine
Director: Professor T.H. Rabbitts


S.M. Bell
V. Speirs
MCPH1, a potential predictor for response to cancer chemotherapy.


P.N. Cockerill
Epigenetic priming of the GM-CSF locus in acute myeloid leukaemia.


G.P. Cook
A.A. Melcher
Targeting tumour antigens and adjuvants to exosomes; novel delivery vehicles for tumour vaccines.


J.E. Crabtree
D.A. Brooke
P.L. Coletta
P.A. Robinson
A novel transgenic model for analysis of Helicobacter pylori induced gastric carcinogenesis.


E.A. de Wynter
G.P. Cook
Towards a better definition of the human haemopoietic stem cell; surface marker expression and functional activity.


A.E. Kiltie
J. Bentley
M.A. Knowles
The influence of DNA double strand break signalling proteins on outcomes following radiotherapy for bladder cancer.


G.I. Sandle
M. Hunter
K. McLennan
Potassium channels as biomarkers of carcinogenesis in human colon.


V. Speirs
M. Cummings
Functional significance of altered prostaglandin signalling in hormone-resistant breast cancer.



FACULTY OF BIOLOGICAL SCIENCES
Dean of the Faculty: Professor A.J. Turner

Institute of Molecular and Cellular Biology
Director: Professor S.W. Homans


P. Robinson
A.A. Melcher
P. Quirke
G.P. Cook
G.E. Blair
Use of post-genomic technologies to discover new targets for colorectal cancer immunotherapy.


G. Bottley
J. Jarvis
G.P. Cook
G.E. Blair
Assessing the role of human papillomavirus (HPV) oncoproteins in regulating cell-mediated immunity: implications for cervical cancer.


M. Harris
Perturbation of b-catenin signalling by the hepatitis C virus NS5A protein: Implications for development of hepatocellular carcinoma.

B.A. Usmani
A.J. Taylor
Expression profiling of the NEP family of metalloproteinases in prostate cancer.


A. Whitehouse
J. Boyne
J. McBride
F. Gould
Cellular genes involved in Kaposis sarcoma associated reactivation and lytic replication.


S.C. Wright
Regulation of the Miz-1 transcription factor.


S.C. Wright
Transcriptional targets of mammalian Mad family proteins.