programme of research

University of Leeds

2007/08

Faculty of Medicine and Health
Dean of the Faculty: Professor E.W. Hillhouse  

The Leeds Institute of Genetics, Health and Therapeutics (LIGHT)
Director: Professor C.P. Wild  


L.J. Hardie         
C.P. Wild            
Investigation of the risks of genetic damage associated with chromoendoscopy in Barrett's Oesophagus patients.  


C.P. Wild             
M.C. Hollstein     
M.N. Routledge
Molecular pathology of lung cancer: environmental causes of tumour suppressor mutations.   


The Leeds Institute of Molecular Medicine
Director: Professor T.H. Rabbitts  


S.M. Bell                 
V. Speirs    
MCPH1, a potential predictor for response to cancer chemotherapy.


P.N. Cockerill       
Epigenetic priming of the GM-CSF locus in acute myeloid leukaemia.  


G.P. Cook            
The role of tumour cell syndecan-1 in conferring susceptibility to natural killer (NK) cells.      


G.P. Cook            
A.A. Melcher         
Targeting tumour antigens and adjuvants to exosomes; novel delivery vehicles for tumour vaccines.     


J.E. Crabtree        
D.A. Brooke         
P.L. Coletta
P.A. Robinson     
A novel transgenic model for analysis of Helicobacter pylori induced gastric carcinogenesis.   


G. Hawcroft            
P.L. Coletta
M.A. Hull   
Prostaglandin E₂-EP4 receptor signalling and colorectal carcinogenesis.    


R. Sarkar             
D. Jayne  
Investigations into the role of cyclin D2.    


E.E. Morrison    
J. Bond
S.M. Bell   
Role of the ASPM protein in cancer.  


E.M.A. Valleley
D.T. Bonthron
Transcriptional regulation of the tumour suppressor gene ZAC. 


P. Quirke          
Report from the YCR Centenary Chair of Pathology.    


Faculty of Biological Sciences
Dean of the Faculty: Professor S.W. Homans  

Institute of Molecular and Cellular Biology
Director: Professor N.M. Hooper  


N. James             
J. Jarvis               
G.P. Cook
G.E. Blair  
Assessing the role of human papillomavirus (HPV) oncoproteins in regulating cell-mediated immunity: implications for cervical cancer.


D. Orchard-Webb   
J. Jarvis
G.P. Cook
G.E. Blair          
Defining the role of CUB domain containing protein 1 (CDCP1) in human cancer. 


M. Harris               
Perturbation of ß-catenin signalling by the hepatitis C virus NS5A protein: Implications for development of hepatocellular carcinoma.  


B.A. Usmani         
A.J. Taylor  
Expression profiling of the NEP family of metalloproteinases in prostate cancer.


B.A. Usmani        
A.J. Turner           
Invasion promoting and suppressing properties of ECE-1 isoforms in prostate cancer.    
 

A. Whitehouse     
J. Boyne
J. McBride
F. Gould   
Cellular genes involved in Kaposi's sarcoma associated reactivation and lytic replication.


S.C. Wright           
Transcriptional targets of mammalian Mad family proteins.