research publications

University of Leeds

2003/4

FACULTY OF MEDICINE, DENTISTRY, PSYCHOLOGY AND HEALTH
Dean of the Faculty: Professor E.W. Hillhouse

School of Medicine
Dean of the School: Professor E.W. Hillhouse

Academic Unit of Pathology
Head of Academic Unit: Prof. P. Quirke

Quirke, P. (2003)
Training and quality assurance for rectal cancer: 20 years of data is enough.
The Lancet Oncology 4, 695-702.

Maughan, N.J., Quirke, P. (2003)
Modern management of colorectal cancer a pathologists view.
Scandinavian Journal of Surgery 92, 11-19.

Maughan, N.J., Quirke, P. (2003)
Genomics in colorectal cancer: godsend or gimmick?
Scandinavian Journal of Gastroenterology 237, 26-29.

FACULTY OF MEDICINE, DENTISTRY, PSYCHOLOGY AND HEALTH
Dean of the Faculty: Professor E.W. Hillhouse

School of Medicine
Dean of the School: Professor E.W. Hillhouse

Academic Unit of Epidemiology and Health Services Research
Head of Academic Unit: Prof. C. Wild

Olliver, J.R., Hardie, L.J., Dexter, S., Chalmers, D. and Wild, C.P. (2003)
DNA damage levels are raised in Barretts oesophageal mucosa relative to squamous epithelium of the oesophagus.
Biomarkers 8, 509-521.

Olliver, J.R., Wild, C.P., Sahay, P., Dexter, S. and Hardie, L.J. (2003)
Chromoendoscopy with methylene blue and associated DNA damage in Barretts oesophagus.
The Lancet 362, 373-374.

Academic Unit of Molecular Medicine
Head of Academic Unit: Prof. D. Bonthron

Dent, J., Hall, G.D., Wilkinson, N., Perren, T.J., Richmond, I., Markham, A.F., Murphy, H. and Bell, S.M. (2003)
Cytogenetic alterations in ovarian clear cell carcinoma detected by comparative genomic hybridisation.
British J Cancer 88(10), 1578-83.

Follows, G.A, Tagoh, H., Lefevre, P., Hodge, D., Morgan, G., and Bonifer, C. (2003)
Epigenetic consequences of AML1-ETO action at the c-FMS locus.
EMBO Journal 22, 27982809.

Coletta, P.L., Mller, A.M., Jones, E.A., Mhl, B., Holwell, S., Clarke, D., Meade, J.L., Cook, G.P., Hawcroft, G., Ponchel, F., Lam, W.K., MacLennan, K.A., Hull, M.A., Bonifer, C. and Markham, A.F. (2004)
Lymphodepletion in the ApcMin/+ mouse model of intestinal tumorigenesis.
Blood 103, 1050-1058.

Wu, A.H., Crabtree, J.E., Bernstein, L., Hawtin, P., Cockburn, M., Tseng, C.C. and Forman, D. (2003)
Role of Helicobacter pylori CagA+ strains and risk of adenocarcinoma of the stomach and the esophagus.
International Journal of Cancer 103, 815821.

Wang, J., Court, M., Jeremy, A.H.T., Aboshkiwa, M.A., Robinson, P.A. and Crabtree, J.E. (2003)
Infection of Mongolian gerbils with Chinese Helicobacter pylori strains.
FEMS Immunology and Medical Microbiology 36, 207-213.

Wang, J., van Doorn, L.J., Robinson, P.A., Ji, X., Wang, D., Wang, Y., Ge, L., Telford, J.L. and Crabtree, J.E. (2003)
Regional variation in vacA alleles of Helicobacter pylori in China.
Journal of Clinical Microbiology 41, 1942-1945.

Stephen, R.L., Crabtree, J.E., Yoshimura, T., Clayton, C.L., Dixon, M.F. and Robinson, P.A. (2003)
Increased levels of zinc finger proteinzFOC1 transcripts in gastric cancer compared to normal gastric tissue.
Journal of Clinical Pathology, Molecular Pathology 56, 167-171.

Kunstmann, E., Hardt, C., Crabtree, J.E., Suerbaum, S. and Epplen, J.T. (2003)
Helicobacter pylori infection: CagA-specific antibodies are associated with clinical outcome, but not with HLA-class II polymorphisms of the host.
International Journal of Medical Microbiology 292, 537-540.

Court, M., Robinson, P.A., Dixon, M.F., Jeremy, A.H.T. and Crabtree, J.E. (2003)
The effect of gender on Helicobacter felis-mediated gastritis, epithelial cell proliferation and apoptosis in the mouse model.
Journal of Pathology 201, 303-311.

Jenks, P.J., Jeremy, A.H.T., Robinson, P.A., Walker, M.M. and Crabtree, J.E. (2003)
Long-term infection with Helicobacter felis and inactivation of the p53 tumour suppressor gene cumulatively enhance the gastric mutation frequency in Big Blue transgenic mice.
Journal of Pathology 201, 596-602.

Dzierzanowska Fangrat, K., Raeiszadeh, M., Dzierzanowska, D., GladkowskaDura, M., Celinska-Cedro, D. and Crabtree, J.E. (2003)
IgG subclass response to Helicobacter pylori and CagA antigens in children.
Clinical and Experimental Immunology 134, 442-446.

Naumann, M. and Crabtree, J.E. (2004)
Helicobacter pylori-induced epithelial signalling in gastric carcinogenesis.
Trends in Microbiology 12, 29-36.

Crabtree, J.E., Court, M., Aboshkiwa, M.A., Jeremy, A.H.T., Dixon, M.F. and Robinson, P.A. (2004)
Gastric mucosal cytokine and epithelial cell responses to Helicobacter pylori in Mongolian gerbils. Journal of Pathology 202, 197-207.

Skliris, G.P., Munot, K., Bell, S.M., Carder, P.J., Lane, S., Horgan, K., Lansdown, M.R.J., Parkes, A.T., Hanby, A.M., Markham, A.F. and Speirs, V. (2003)
Reduced expression of oestrogen receptorb in invasive breast cancer and its re-expression using DNA methyltransferase inhibitors in a cell line model.
Journal of Pathology 201, 213-220.

Burdall, S.E., Hanby, A.M., Lansdown, M.R.J. and Speirs, V. (2003)
Breast cancer cell lines: friend or foe?
Breast Cancer Research 5, 89-95.

Academic Unit of Oncology and Haematology
Head of Academic Unit: Prof. P.J. Selby

Musa, H., Orton, C., Morrison, E.E. and Peckham, M. (2003)
Microtubule assembly in cultured myoblasts and myotubes following nocodazole induced microtubule depolymerisation.
Journal of Muscle Research and Cell Motility 24(4-6), 303-310.

FACULTY OF BIOLOGICAL SCIENCES
Chairman of Faculty: Professor K.T. Holland

School of Biochemistry and Molecular Biology
Head of the School: Professor A.J. Turner

Bentley, J., Itchayanan, D., Barnes, K., McIntosh, E., Tang, X., Downes, C.P., Holman, G.D., Whetton, A.D., Owen-Lynch, P.J. and Baldwin, S.A. (2003)
Interleukin-3-mediated cell survival signals include phosphatidylinositol 3-kinase-dependent translocation of the glucose transporter GLUT1 to the cell surface.
Journal of Biological Chemistry 278, 39337-39348.

Fox, E.J., Stubbs, S.A., Kyaw Tun, J., Leek, J.P., Markham, A.F. and Wright, S.C. (2004)
PRELI (protein of relevant evolutionary and lymphoid interest) is located within an evolutionarily conserved gene cluster on chromosome 5q34-q35 and encodes a novel mitochondrial protein.
Biochemical Journal 378, 817-825.

Fox, E.J. and Wright, S.C. (2003)
The transcriptional repressor gene Mad3 is a novel target for regulation by E2F1.
Biochemical Journal 370, 307-313.

Kime, L. and Wright, S.C. (2003)
Mad4 is regulated by a transcriptional repressor complex that contains Miz-1 and c-Myc.
Biochemical Journal 370, 291-298.

YORKSHIRE CANCER RESEARCH PHOTODYNAMIC THERAPY GROUP
Centre for Photobiology and Photodynamic Therapy
Principal Investigator: Professor S.B. Brown

Jones, H.J., Vernon, D.I. and Brown, S.B. (2003)
Photodynamic therapy effect of m-THPC (Foscan) in vivo: correlation with pharmacokinetics.
British Journal of Cancer 89, 398-404.

Brown, S.B. (2003)
The role of light in the treatment of non-melanoma skin cancer using methyl aminolevulinate.
Journal of Dermatological Treatment 14, Suppl 3, 11-14.

Sudworth, C.D., Stringer, M.R., Cruse-Sawyer, J.E. and Brown S.B. (2003)
Fluorescence microspectroscopy technique for the study of intracellular protoporphyrin IX dynamics.
Applied Spectroscopy 57, 682-688.