research publications

University of Leeds

2004/5

FACULTY OF MEDICINE AND HEALTH
Dean of the Faculty: Professor E.W. Hillhouse

The Institute of Molecular Medicine, Epidemiology and Cancer Research
Director: Professor P.J. Selby

Academic Unit of Molecular Medicine
Director: Professor D.T. Bonthron

Trimborn, M., Bell, S.M., Felix, C., Rashid, Y., Jafri, H., Griffiths, P.D., Neumann, L.M., Krebs, A., Reis, A., Sperling, K., Neitzel, H. and Jackson, A.P. (2004)
Microcephalin is a regulator of chromosome condensation.
American Journal of Human Genetics 75, 261-266.

Coletta, P.L., Muller, A.M., Jones, E.A., Muhl, B., Holwell, S., Clarke, D., Meade, J.L., Cook, G.P., Hawcroft, G., Ponchel, F., Lam, W.K., MacLennan, K.A., Hull, M.A., Bonifer, C., Markham, A.F. (2004)
Lymphodepletion in the ApcMin/+ mouse model of intestinal tumorigenesis.
Blood 103, 1050-1058.

Johnson, B.V., Bert, A.G., Ryan, G.R,, Condina, A. and Cockerill, P.N. (2004)
GM-CSF enhancer activation requires cooperation between NFAT and AP-1 elements and is associated with extensive nucleosome reorganisation.
Molecular and Cellular Biology 24, 7914-7930.

Speirs, V., Carder, P.J., Lane, S., Dodwell, D., Lansdown, M.R.J. and Hanby, A.M. (2004)
Oestrogen receptor b: what it means for patients with breast cancer.
Lancet Oncology 5, 174-181

Academic Unit of Oncology & Haematology
Head of Academic Unit: Professor P.J. Selby

Heath, R. M., Jayne, D. G., O'Leary, R., Morrison, E. E. and Guillou, P. J. (2004).
Tumour induced apoptosis in human mesothelial cells: a mechanism of peritoneal invasion by Fas ligand/Fas interaction.
British Journal of Cancer 90, 1437-1442.

Hale, G., Rebello, P., Brettman, L.R., Fegan, C., Kennedy, B., Kimby, E., Leach, M., Lundin, J., Mellstedt, H., Moreton, P., Rawstron, A.C., Waldmann, H., Osterburg, A., Hillmen, P. (2004)
Blood concentrations of alemtuzumab and antiglobulin responses in patients with chronic lymphocytic leukaemia following intravenous or subcutaneous routes of administration.
Blood 104, 948-955.

FACULTY OF BIOLOGICAL SCIENCES
Dean of the Faculty: Professor A.J. Turner

School of Biochemistry and Microbiology
Acting Head of the School: Professor R A Killington

Dawson, L.A., Maitland, N.J., Turner, A.J. & Usmani, B.A. (2004)
Stromal-epithelial interactions influence prostate cancer cell invasion by altering the balance of metallopeptidase expression.
British Journal of Cancer 90, 1577-82.

Yorkshire Cancer Research Photodynamic Therapy Group
Centre for Photobiology and Photodynamic Therapy

A multidisciplinary approach to the development of photodynamic therapy for cancer
Principal Investigator: Professor S B Brown

Walker, I., Vernon, D.I. and Brown, S.B. (2004)
The solid phase conjugation of purpurin-18 with a synthetic targeting peptide.
Bioorganic and Medicinal Chemistry Letters 14, 441-443.

Kelty, C.J., Ackroyd, R., Brown, N.J., Brown, S.B. and Reed, W.R. (2004)
Comparison of high versus low dose 5-aminolaevulinic acid for photodynamic therapy of Barrett's oesophagus.
Surgical Endoscopy 18, 452-458.

Walker, I., Gorman, S.A., Cox, R.D., Vernon, D.I., Griffiths, J. and Brown, S.B. (2004)
A comparative analysis of phenothiazinium salts for the photosensitisation of murine fibrosarcoma (RIF-1) cells in vitro.
Photochemical and Photobiological Sciences 3, 653-659.

Brown, S.B., Brown, E.A. and Walker I. (2004)
The present and future role of photodynamic therapy in oncology.
Lancet Oncology 5, 1038-1043.

Van den Aker, J.T., Boot, K., Vernon, D.I., Brown, S.B., Groenendijk, L., van Rhoon, G.C. and Sterenbourg, H.J. (2004)
Effect of elevating the skin temperature during topical ALA application on in vitro ALA penetration through mouse skin and in vivo PpIX production in human skin.
Photochemical and Photobiological Sciences 3, 263-267.