RESEARCH

Directly or indirectly, cancer will touch everyone's lives. There is no greater or more worthwhile challenge than the ongoing battle to develop and improve anti-cancer treatments, for everyone's sake.

programme of research


University of Sheffield

2001/2


YCR Director: Professor B.W. Hancock

Central Research Facilities


Flow Cytometry Unit
J. Lawry
M.O. Smith
Fluorescent activated cell sorter (FACS)

Clinical Trials Centre
R.E. Coleman
B.W. Hancock
Clinical trials service



Division of Genomic Medicine, Section of Oncology & Pathology(YCR Institute for Cancer Studies, YCR Academic Unit of Clinical Oncology, Academic Unit of Pathology)

YCR Institute for Cancer Studies

M. Meuth
Genetic instabilities and cancer

D.W. Hammond
Ms M. Baird
Ms C. Wardle
Ms K. Rees
Identification of regions of DNA amplification and deletion in NHL

P.R.M. Dobson
B.L. Brown (Section ofFunctional Genomics)
The role and action of ceramide in cytokine-induced apoptosis

J.A. Royds
C. E. Lewis
C. Parker
Response of tumour cells to hypoxia: role of p53 and NFkB


YCR Academic Unit of Clinical Oncology

R.E. Coleman
B.W. Hancock
P.C. Lorigan
M. Marples
M.H. Robinson
Clinical research programme


Academic Unit of Pathology

B. Burke
M. Wells
C.E. Lewis
Role of EGR-1 in macrophage responses to hypoxia

M. Wells
Putative tumour suppressor gene PTEN in thedevelopment of endometrial carcinoma


Division of Clinical Sciences (N)
Section of Medicine

S. MacNeil
J.W. Haydock (Department of Engineering Materials)
P.C. Lorigan (Division of Genomic Medicine, YCR Academic Unit of Clinical Oncology)
Examination of early melanoma metastasis


Department of Biomedical Science

P. Andrews
C. Duran
J. Walsh
C. Pigott
P. J. Talley (North Trent Cytogenetics Service, Sheffield Childrens Hospital)
Different action of malignant stem cells; mechanisms of restriction


Department of Molecular Biology & Biotechnology

C. Price
Cut5/Rad4 protein in initiating the DNAstructure

Characterisation of the fission yeastDrc1p homologue