RESEARCH

Directly or indirectly, cancer will touch everyone's lives. There is no greater or more worthwhile challenge than the ongoing battle to develop and improve anti-cancer treatments, for everyone's sake.

programme of research


University of Sheffield

2005/6



DIVISION OF GENOMIC MEDICINE

YCR Director of Cancer Research: Professor B W Hancock

SECTION OF ONCOLOGY & PATHOLOGY
(YCR Institute for Cancer Studies, Academic Unit of Clinical Oncology, Academic Unit of Pathology)

YCR Institute for Cancer Studies

A. Cox

The effect of single nucleotide polymorphisms on clinical outcome and survival in the FOCUS clinical trial of metastatic colorectal cancer.


T. Helleday

Molecular mechanism for genetic instability caused by inactivation of poly (ADP-ribose) polymerase.


M. Meuth

Genetic Instability and Cancer.


C.M. Sanders

A structural investigation of the papillomavirus replication initiation complexes.




Academic Unit of Pathology


C. Lewis

Development of a macrophage-based system to target therapeutic viruses to prostate cancer.


C. Lewis

Novel use of hypoxia response promoters in Salmonella to target genes to hypoxic.




Academic Unit of Infection and Immunity


A. Heath

Novel, highly immunogenic ganglioside based cancer vaccines.


A. Heath
J. Cariring

Improved idiotype vaccines for cancer.




Division of Clinical Sciences (S)
Academic Unit of Urology


C.L. Eaton

The role of Osteoprotegerin on prostate cancer survival.




Academic Unit of Surgical Oncology


C.A. Staton

The relationship between tissue factor and vascular endothelial growth factor in breast cancer.




Medical Imaging and Medical Physics


W.B. Tindale

FDG dual-headed PET identifies those patients with non-small cell lung cancer who are suitable for surgery?




Department of Biomedical Science

P.W. Andrews

A screen of candidate regulatory genes that may play a role in the progression of testicular germ cell tumours.


P.W. Andrews

Regulation of pluripotency in malignant stem cells.