research publications

University of Sheffield

2006/7

Faculty of Medicine
School of Medicine and Biomedical Sciences

SECTION OF ONCOLOGY

YCR Institute for Cancer Studies

Cox, A. Dunning, A.M., Garcia-Closas, M. et al., on behalf of the Breast Cancer Association Consortium (2007)
A common coding variant in CASP8 is associated with breast cancer risk.
Nature Genetics, 39(3), 352-358.

Balasubramanian, S.P., Azmy, I.A.F., Higham, S.E., Wilson, A.G., Cross, S.S., Cox, A., Brown, N.J. and Reed, M.W. (2006).
Interleukin gene polymorphisms and breast cancer: a case control study and systematic literature review.
BMC Cancer, 6, 188.

The Breast Cancer Association Consortium (2006)
Commonly studied single-nucleotide polymorphisms and breast cancer: results from the Breast Cancer Association Consortium.
Journal of the National Cancer Institute, 98(19), 1382-1396.

Bryant, H.E., Helleday, T. (2006)
Inhibition of poly(ADP-ribose) polymerase activates ATM which is required for subsequent homologous recombination repair.
Nucleic Acids Research, 34(6), 1685-1691.

Renglin Lindh, A., Rafii, S., Schultz, N., Cox, A., Helleday, T. (2006)
Mitotic defects in XRCC3 variants T241M and D213N and their relation to cancer susceptibility.
Human Molecular Genetics, 15(7), 1217-1224.

Bryant, H.E., Ying, S., Helleday, T. (2006)
Homologous recombination is involved in repair of chromium-induced DNA damage in mammalian cells.
Mutation Research, 599(1-2), 116-123.

Roupret M, Hupertan V, Yates DR, Catto JW, Rehman I, Meuth M, Ricci S, Lacave R, Cancel-Tassin G, de la Taille A, Rozet F, Cathelineau X, Vallancien G, Hamdy FC, Cussenot O. (2007)
Molecular detection of localized prostate cancer using quantitative methylation-specific PCR on urinary cells obtained following prostate massage.
Clin Cancer Res. 13, 1720-1725.

Yates, D., Rehman, I., Cross, S., Meuth, M., Hamdy, F., Catto, J.W.F. (2006).
Methylational urinalysis: a prospective study of bladder cancer patients and age stratified benign controls.
Oncogene, 25, 1984-1988.

Rodriguez, R. and Meuth, M. (2006).
Chk1 and p21 cooperate to prevent apoptosis during DNA replication fork stress.
Mol. Biol. Cell, 17, 402-412.

Dhawan, D., Hamdy, F., Rehman, I., Patterson, J., Cross, S., Feeley, K., Stephenson, Y., Meuth, M., Catto, J. (2006).
Evidence for the early onset of aberrant promoter methylation in urothelial carcinoma.
J Pathol. 209, 336-343.

Catto, J.W., Hartmann, A., Stoehr, R., Bolderson, E., Rehman, I., Rosario, D.J., Hamdy, F. C., Meuth, M. (2006).
Multifocal urothelial cancers with the mutator phenotype are of monoclonal origin and require panurothelial treatment for tumour clearance.
J. Urol.175, 2323-2330.

Castella S., Bingham G. and Sanders C. (2006)
Common determinants in DNA melting and helicase-catalysed DNA unwinding by papillomavirus replication protein E1.
Nucleic Acids Res. 34: 3008-19.

Castella S., Burgin, D. and Sanders C. (2006)
Role of ATP hydrolysis in the DNA translocase activity of the bovine papillomavirus (BPV-1) E1 helicase.
Nucleic Acids Res. 34: 3731-41.

Castella S. and Sanders C. (2006).
High specific activity probes and a high-resolution in-gel photo cross-linking assay for protein-DNA complexes.
Analytical Biochemistry, 359: 203-209.


Academic Unit of Ophthalmology and Orthoptics

Cross, N.A., Murray, A.K., Rennie, I.G., Ganesh, A., Sisley, K (2006).
Instability of microsatellites is an infrequent event in uveal melanoma
Melanoma Res, 13, 435-40.


Academic Unit of Pathology

Bingle, L., Cross, S.S., High, A.S., Wallace, W.A., Rassl. D., Yuan, G., Hellstrom, I., Campos, M.A., Bingle, C.D.
WFDC2 (HE4): a potential role in the innate immunity of the oral cavity and respiratory tract and the development of adenocarcinomas of the lung.
Respir Res. 2006 Apr 6;7:61.


Academic Unit of Clinical Oncology

Zhu, Y.M., Bagstaff, S.M., Woll, P.J. (2006).
Production and upregulation of granulocyte chemotactic protein-2/CXCL6 by IL-1beta and hypoxia in small cell lung cancer.
Br J Cancer. 2006 Jun 19;94(12):1936-41.

Horsman JM, Thomas J, Hough R, Hancock BW.
Primary bone lymphoma: a retrospective analysis.
Int J Oncol. 2006 Jun;28(6):1571-5.

Osama Al-Assar, Karen S. Rees-Unwin, Lia P. Menasce, Rachel E. Hough, John R. Goepel, David W. Hammond and Barry W. Hancock.
Transformed diffuse large B-cell lymphomas with gains of the discontinuous 12q12-14 amplicon display concurrent deregulation of CDK2, CDK4 and GADD153 genes.
British Journal of Haematology, 2006. 133, 612-621.


SECTION OF INFECTION, INFLAMMATION AND IMMUNITY
Academic Unit of Infectious Diseases

Skotheim RI, Autio R, Lind GE, Kraggerud SM, Andrews PW, Monni O, Kallioniemi O, Lothe RA. (2006)
Novel genomic aberrations in testicular germ cell tumors by array-CGH, and associated gene expression changes.
Cell Oncol. 28, 315-326.


DEPARTMENT OF BIOMEDICAL SCIENCE

Baker, D.E.C., Harrison, N.J., Maltby, E., Smith, K., Moore, H.D., Shaw, P.J., Heath, P.R., Holden, H., Andrews, P.W. (2007)
Adaptation to culture of human embryonic stem cells and oncogenesis in vivo.
Nature Biotechnology 25, 207 215

Wood, J.D., Landers, J.A., Bingley, M., McDermott, C.J., Thomas-McArthur, V., Gleadall. L.J., Shaw, P.J., Cunliffe, V.T. (2006).
The microtubule-severing protein Spastin is essential for axon outgrowth in the zebrafish embryo.
Hum Mol Genet. 2006 Sep 15;15(18):2763-71.