research publications

University of York

2001/2

Yorkshire Cancer Research Cancer Research Unit
Director of Unit: Prof N.J. Maitland

Maitland, N.J., Macintosh, C.A., Hall, J., Sharrard, R.M., Quinn, G. and Lang, S. (2001)
In vitro models to study cellular differentiaton and function in human prostate cancers.
Radiation Research 155, 133-142.

Scott, L.J., Clarke, N.W., George, N.J.R., Shanks, J.H., Testa, N.G. and Lang, S.H. (2001)
Interactions of human prostatic epithelial cells with bone marrow endothelium: binding and invasion.
British Journal of Cancer 84, 1417-1423.

Lang, S.H., Stark, M., Villette, J.M. and Maitland, N.J. (2001)
Prostate epithelial cell lines form spheroids with evidence of glandular differentiation in three dimensional matrigel cultures.
British Journal of Cancer 85, 590-599.

Lang, S.H., Stark, M., Collins, A., Paul, A.B., Stower, M.J. and Maitland, N.J. (2001)
Experimental prostate epithelial morphogenesis in response to stroma and three dimensional Matrigel culture
Cell Growth and Differentiation 12, 631-640.

Hall, J., Maitland, N.J., Stower, M., Lang, S. (2001)
Primary Prostate Stromal Cells Modulate the Morphology and Migration of Primay Prostate Epithelial Cells in Type 1 Collagen Gels.
Cancer Research 62, 58-62

Collins, A.T., Habib, F.K., Maitland, N.J. and Neal, D.E. (2001)
Identification and isolation of human prostate stem cells based ona2b1integrin expression.
J Cell Science 114, 3865-3872.

Bretland, A.J., Lawry, J. and Sharrard, R.M. (2001)
A study of death by anoikis in cultured epithelial cells.
Cell Proliferation 34, 199-210.

Moroz, O.V., Antson, A.A., Murshudov, G.N., Maitland, N.J., Dodson, G.G., Wilson, K.S., Skibshoj, I., Lukanidin, E.M., Bronstein, I.B. (2001)
The three-dimensional structure of human S100A12.
Acta CrystallogrD Biol Crystallogr 57(Pt 1), 20-29.

Svetlana, T., Scott, D.J., Maitland, N.J., Lukanidin, E.M., Bronstein, I.G., (2001)
The dimerisation interface of metastasis associated protein S100A4 (Mts1): in vivo and in vitro studies.
Journal of Biological Chemistry 276, 24212-24222.


Yorkshire Cancer Research P53 Research Laboratory
Director of Unit: Prof J. Milner

Jiang, M., Holgate, R., Axe, T.J., Rubbi, C.P., Okorokov, A.L., Mee, T.R., and Milner, J. (2001)
p53 binds the nuclear matrix in normal cells: binding involves the proline-rich domain of p53 and increases following genotoxic stress.
Oncogene 20, 5449-5458.

Rubbi, C.P., and Milner, J. (2001)
Analysis of nucleotide excision repair by detection of single-stranded DNA transients.
Carcinogenesis 22, 1789-1796.

Okorokov, A.L., Rubbi, C.P., Metcalfe, S.M., and Milner, J. (2002)
The interaction of p53 with the nuclear matrix is mediated by F-actin and modulated by DNA damage.
Oncogene 21, 356-367.

Okorokov, A.L., Warnock, L.J., and Milner, J. (2002)
Effect of wild type, S15 and R175H p53 proteins on DNA end-joining in vitro: potential mechanism of DNA double-strand break repair modulation.
Carcinogenesis 23, 549-557