Directly or indirectly, cancer will touch everyone's lives. There is no greater or more worthwhile challenge than the ongoing battle to develop and improve anti-cancer treatments, for everyone's sake.
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research publications
University of York
2002/3
Yorkshire Cancer Research Cancer Research Unit
Director of Unit: Prof N.J. Maitland
Lang, S.H., Hyde, C., Reid, I.N., Hitchcock, I.S., Hart, C.A., Gordon Bryden, A.A., Villette, Jean-Marie., Stower, M.J. and Maitland, N.J., (2002)
Enhanced Expression of Vimentin in Motile Prostate Cell Lines and in Poorly Differentiated and Metastatic Prostate Carcinoma.
The Prostate 52: 253-263
Davies, H., Bignell, G.R., Cox, C., Stephens, P., Bottomley, W., Davis, N., Hall, S., Hawes, R., Stevens, C., Shipley, J., Maitland, N.J., Paterson, H., Marais, R., Wooster, R., Stratton, M.R. and Futreal, P.A., (2002)
Mutations of the BRAF gene in human cancer.
Nature 417: 949-954
Lundqvist, A., Noffz, G., Pavlenko, M., Saeboe-Larssen, S., Fong, T., Maitland, N.J. and Pisa, P., (2002)
Nonviral and Viral Gene Transfer into Different Subsets of Human Dendritic Cells Yield Comparable Efficiency of Transfection.
Journal of Immunotherapy 26: (6) 445-454
Lundqvist, A., Choudhury, A., Nagata, T., Andersson, T., Quinn, G., Fong, T., Maitland, N.J., Pattersson, S., Paulie, S. and Pisa, P., (2002)
Recombinant Adenovirus Vector Activates and Protects Human Monocyte-Derived Dendritic Cells from Apoptosis.
Human Gene Therapy 13: 1541-1549
Yorkshire Cancer Research P53 Research Group
Director of Unit: Professor J. Milner
Jiang M, and Milner J. (2003)
Bcl-2 constitutively suppresses p53-dependent apoptosis in colorectal cancer cells.
Genes & Development 17, 832-837.
Rubbi CP, and Milner J. (2003)
p53 guardian of a Genome's Guardian?
Cell Cycle 2, 18-19.
Rubbi, C.P. and Milner, J. (2003)
p53 is a chromatin accessibility factor for nucleotide excision repair of DNA damage.
EMBO J 22, 975-986.
Jiang, M. and Milner, J. (2002)
Selective silencing of viral gene expression in HPV-positive human cervical carcinoma cells treated with siRNA, a primer of RNA interference.
Oncogene 21, 6041-6048.
Stein, T., Crighton, D., Warnock, L.J., Milner, J. and White, R. (2002)
Several regions of p53 are involved in repression of RNA polymerase III transcription.
Oncogene 21, 5540-5547.
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