research publications

University of York

2003/4

YCR CANCER RESEARCH UNIT
Director: Professor N.J. Maitland

Stanbridge, L., Dussupt, V., Maitland, N.J. (2003)
Baculoviruses as Vectors for Gene Therapy against Human Prostate Cancer.
Journal of Biomedicine and Biotechnology 1-13

Burns, J.E., Burn, C.L., Hernandez-Ramon, E., Schmitz, C., Lloansi Vila, A., Maitland, N.J. (2003)
Forms and Functions of Papillomavirus E2 Proteins.
Recent Research in Biochemistry 4: 795-823

Collins, A.T., Maitland, N.J. (2003)
Stem Cells and Cancer: The Origin of Prostate Carcinoma (Prostate Cancer Series: Part One)
Cancer Topics 11, 12: 1-5

Rippon, H., Maitland, N.J. (2003)
Human Prostate Specific Transglutaminase: a highly specific differentiation linked Prostatic Marker
Prostate Cancer and Prostatic Diseases 6: 90-104

Moroz, O.V., Antson, A.A., Grist, S.J., Maitland, N.J., Dodson, G.G., Wilson, K.S., Lukanidin, E., Bronstein, I.B. (2003)
Structure of the human S100A12-copper complex: implications for host-parasite defence
Acta Crystallographica Section D 59: 859-867

Dawson, L.A., Maitland, N.J., Turner, A.J., Usmani, B.A. (2003)
Stromal-epithelial interactions influence prostate cancer cell invasion by altering the balance of metallopeptidase expression
European Urology Supplements 2: 6, 173

Sharrard, R.M., Maitland, N.J. (2003)
Alterations in the activation pathways of protein kinase B and Erk in the progression to metastasis of human prostate cancer
European Urology Supplements 2: 6, 162

Spalton, J.C., Maitland, N.J., Sharrard, R.M. (2003)
Insulin-like growth factor 1, the protein kinase B pathway and the progressssion to metastasis of prostate cancer
European Urology Supplements 2: 6, 33

Birnie, R., Maitland, N.J. (2003)
Development of a novel androgen responsive model of prostate epithelium
European Urology Supplements 2: 6, 29

Scaltriti, M., Bettuzzi, S., Sharrard, R.M., Caporali, A., Caccoma, A.E., Maitland, N.J. (2003)
Clusterin over-expression in both malignant and non-malignant prostate epithelial cells induces cell cycle arrest and apoptosis
European Urology Supplements 2: 6, 6

Maitland, N.J. (2003)
Exploitation of Prostate Gene Expression to Develop Targeted Therapies
Acta BioMedica 74: 105-106


Yorkshire Cancer Research P53 Research Group
Director of Unit: Professor J. Milner

Allison, S.J. and Milner, J. (2003)
Loss of p53 has site-specific effects on histone H3 modifications, including serine 10 phosphorylation important for maintenance of ploidy.
Cancer Research 63, 6674-6679.

Rubbi, C.P. and Milner, J. (2003)
P53 is a chromatin accessibility factor for nucleotide excision repair of DNA damage.
EMBO Journal 22, 975-986.

Crighton, D., Woiwode, A., Zhang, C., Mandavia, N., Morton, J.P., Warnock, L.J., Milner, J., White, R.J. and Johnson, D.L. (2003)
P53 represses RNA polymerase III transcription by targeting the TBP and inhibiting promoter occupancy by TFIIIB.
EMBO Journal 22, 2810-2820.

Rubbi, C.P. and Milner, J. (2003)
Disruption of the nucleolus mediates stabilisation of p53 in response to DNA damage and other stresses.
EMBO Journal 22, 6068-6077.

Milner, J. (2003)
RNA interference for treating cancers caused by viral infection.
Expert Opinion on Biological Therapy 3, 1471-2598.

Jiang, M. and Milner, J. (2003)
Bcl-2 constitutively suppresses p53-dependent apoptosis in colorectal cancer cells.
Genes and Development 17, 832-837.


Department of Chemistry

Franci, X., Martina, S. L. X., McGrady, J. E., Webb, M. R., Donald, C., Taylor, R. J. K. (2003)
A comparison of the Still-Gennari and Ando HWE-methodologies with ,-unsaturated aldehydes; Unexpected results with stannyl substituted systems.
Tetrahedron Lett. 44, 7735-7740.