research publications

University of York

2005/6


Coverley, D., Laman, H. and Laskey, R.A. (2002)
Distinct roles for cyclins E and A during DNA replication complex assembly and activation
Nat Cell Biol, 4, 523-528

Coverley, D., Marr, J. and Ainscough, J. (2005)
Ciz1 promotes mammalian DNA replication
J Cell Sci, 118, 101-112.

Ottini, L., Falchetti, M., Saieva, C., De Marco, M., Masala, G., Zanna, I., Paglierani, M., Giannini, G., Gulino, A., Nesi, G., Mariani Costantini, R. and Palli, D. (2004)
MRE11 expression is impaired in gastric cancer with microsatellite instability
Carcinogenesis, 25, 2337-2343

Rave-Harel, N., Kerem, E., Nissim-Rafinia, M., Madjar, I., Goshen, R., Augarten, A., Rahat, A., Hurwitz, A., Darvasi, A. and Kerem, B. (1997)
The molecular basis of partial penetrance of splicing mutations in cystic fibrosis
Am J Hum Genet, 60, 87-94


YCR Cancer Research Unit
Director of Unit: Professor N.J. Maitland

Maitland, N.J., Collins, A.T. (2005)
Making order out of heterogeneity: A tumour stem cell hypothesis for the origins of prostate cancer
BJU International 96: 1219-1223

Collins, A.T., Berry, P.A., Hyde, C., Stower, M.J., Maitland, N.J., (2005)
Prospective Identification of Tumorigenic Prostate Cancer Stem Cells
Cancer Research 65: (23) 10946-10951

MacRae, E.J., Giannoudis, A., Ryan, R., Brown, N.J., Hamdy, F.C., Maitland, N.J., Lewis, C.E. (2005)
Gene Therapy for Prostate Cancer: Current Strategies and New Cell-Based Approaches
The Prostate 1-25

Burns, J., Maitland, N.J. (2005)
Human Papillomaviruses and cancer
Microbiology Today Aug 05 116-120

Riddick, A.C.P., Shukla, C.J., Pennington, C.J., Bass, R., Nuttall, R.K., Hogan, A.K., Sethia, K, Ellis, V., Collins, A.T., Maitland, N. J., Ball, R.Y., and Edwards, D.R. (2005)
Identification of degradome components associated with prostate cancer progression by expression analysis of human prostatic tissues
BJC 92: 2171-2180

Lewis, J.L., Maitland, N.J. (2005)
Signals of Success
European Biopharmaceutical Review Winter 2005, 58-65

Patents

UK Patent Application
Cancer Stem Cell Patent Number 0406215.4

European Patent Application
Cell Culture Method for Obtaining Prostate-like Acini Patent Number 02755137.3

UK Divisional Patent Application
Cell Model Patent Number 0412824.5

International Patent Application
Humanised Baculovirus Patent Number PCT/GB2005/004465

European Patent Application
Humanised Baculovirus Patent Number 02764996.1

UK Patent Application
Humanised Baculovirus II Patent Number 0425739.0

UK Patent Application
Cell Panel Patent Number 0426701.9

UK Patent Application
Stem Cell Markers 1 Patent Number 0515305.1

UK Patent Application
Stem Cell Markers 2 Patent Number 0515307.7

UK Patent Application
Stem Cell Markers 3 Patent Number 0515308.5

UK Patent Application
Stem Cell Markers 4 Patent Number 0515309.3

UK Patent Application
Stem Cell Markers 5 Patent Number 0515310.1


Yorkshire Cancer Research p53 Research Group
Director of Unit: Professor J. Milner

Warnock, L.J., Raines, S.A., Mee, T.R. and Milner, J. (2005)
Role of phosphorylation in p53 acetylation and PAb421 epitope recognition in baculoviral and mammalian expressed proteins
The FEBS Journal 272, 1669-1675

Jiang, M., Arzumanov, A.A., Gait, M.J. and Milner, J. (2005)
A bi-functional siRNA construct induces RNA interference and also primes PCR amplification for its own quantification
Nucleic Acids Research 33, e151

Bochkareva, E., Kaustov, L., Ayed, A., Yi, G-S., Lu, Y., Pineda-Lucena, A., Liao, J.C.C., Okorokov, A.L., Milner, J., Arrowsmith, C.H. and Bochkarev, A. (2005)
Single-stranded DNA mimicry in the p53 transactivation domain interaction with replication protein A
Proceedings of the National Academy of Sciences 102, 15412-15417

Ford, J., Jiang, M. and Milner, J. (2005)
Cancer-specific functions of SIRT1 enables human epithelial cancer cell growth and survival
Cancer Research 65, 10457-10463

Lynch, C.L. and Milner, J. (2006)
Loss of one p53 allele results in four-fold reduction of p53 mRNA and protein: a basis for P53 haplo-insufficiency
Oncogene [Epub ahead of print]