research publications

University of York

2006/7

Department of Biology
Mammalian DNA Replication Research Group
Principal Investigator: Dr. Dawn Coverley

Coverley D, Marr J, Ainscough J. (2005)
Ciz1 promotes mammalian DNA replication.
Journal of Cell Science 118, 101-12

Ainscough JF, Rahman FA, Sercombe H, Sedo A, Gerlach B, Coverley D. (2007)
C-terminal domains deliver the DNA replication factor Ciz1 to the nuclear matrix.
Journal of Cell Science 120, 115-24


YCR Cancer Research Unit
Director: Professor N J Maitland

Lang SH, Smith J, Hyde C, Macintosh C, Stower M, Maitland NJ.
Differentiation of prostate epithelial cell cultures by matrigel/ stromal cell glandular reconstruction.
In Vitro Cell Dev Biol Anim. 2006: 42:273-80.

Sharrard RM, Maitland NJ.
Regulation of protein kinase B activity by PTEN and SHIP2 in human prostate-derived cell lines.
Cell Signal. 2007: 19:129-38.

Keenan ID, Sharrard RM, Isaacs HV
FGF signal transduction and the regulation of Cdx gene expression
Developmental Biology. 2006: 299:478-488

Chapel-Fernandes S, Jordier F, Lauro F, Maitland N, Chiaroni J, de Micco P, Mannoni P, Bagnis C.
Use of the PSA enhancer core element to modulate the expression of prostate- and non-prostate-specific basal promoters in a lentiviral vector context.
Cancer Gene Ther. 2006: 13:919-29.

Heer R, Collins A T, Robson C N, Shenton B K, Leung H Y
KGF suppresses a2b1 integrin function and promotes differentiation of the transient amplifying population in human prostatic epithelium
Journal of Cell Science. 2006: 119:1416-24

Dawson LA, Maitland NJ, Berry P, Turner AJ, Usmani BA.
Expression and localization of endothelin-converting enzyme-1 in human prostate cancer.
Exp Biol Med. 2006: 231:1106-10.

Collins AT, Maitland NJ.
Prostate cancer stem cells.
Eur J Cancer. 2006: Jun; 42:1213-8.

MacRae EJ, Giannoudis A, Ryan R, Brown NJ, Hamdy FC, Maitland N, Lewis CE.
Gene therapy for prostate cancer: current strategies and new cell-based approaches.
The Prostate. 2006: 66:470-94.

Maitland NJ.
Getting DNA into cells.
European Urology Today. 2006: 18:23-4.

Maitland NJ, Collins AT.
Prostate Cancer: New Designs on Treatment Development.
Oncology News. 2006:1:5-7.

Maitland NJ.
New treatments for an old mans disease.
The House Magazine. 2007: Jan:1202:35-7


YORKSHIRE CANCER RESEARCH P53 RESEARCH GROUP
Director of Unit: Professor J. Milner

Lynch, C.L. and Milner, J. (2006)
Loss of one p53 allele results in four-fold reduction of p53 mRNA and protein: a basis for P53 haplo-insufficiency.
Oncogene 25. 3463-3470.

Okorokov, A.L., Sherman, M.B., Plisson, C., Grinkevich, V., Sigmundsson, K., Selivanova, G., Milner, J. and Orlova, E. (2006)
The structure of p53 tumour suppressor protein reveals the basis for its functional plasticity.
EMBO Journal 25. 5191-5200.