Directly or indirectly, cancer will touch everyone's lives. There is no greater or more worthwhile challenge than the ongoing battle to develop and improve anti-cancer treatments, for everyone's sake.
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research publications
University of York
2007/08
Department of Biology
Mammalian DNA Replication Research Group
Principal Investigator: Dr. Dawn Coverley
Ainscough JF, Rahman FA, Sercombe H, Sedo A, Gerlach B, Coverley D. (2007)
C-terminal domains deliver the DNA replication factor Ciz1 to the nuclear matrix.
Journal of Cell Science 120, 115-24
Rahman F A, Ainscough JF-X, Copeland N, Coverley D (2007)
Cancer-associated mis-splicing of exon 4 influences the sub-nuclear distribution of the DNA replication factor CIZ1
Human Mutation 28, 993-1004
YCR CANCER RESEARCH UNIT
Director of Unit: Professor N. J. Maitland
Sharrard, R.M. and Maitland, N.J. (2007)
Regulation of protein kinase B activity by PTEN and SHIP2 in human prostate-derived cell lines.
Cellular Signalling 19 (1): 129-138
Maitland, N.J., Bryce, S., Stower, M.J. and Collins, A.T. (2007)
Prostate cancer stem cells: a target for new therapies.
Ernst Schering Found Symposium Proc. 5: 155-79
Keith,W.N., Tomson, C.M., Howcroft, J., Maitland, N.J. and Shay, J.W. (2007)
Seeding drug discovery: integrating telomerase cancer biology and cellular senescence to uncover new therapeutic opportunities in targeting cancer stem cells.
Drug Discovery Today 12: 611-21
YORKSHIRE CANCER RESEARCH P53 RESEARCH UNIT
Director of Unit: Professor J. Milner
Allison, S.J. and Milner, J. (2007)
SIRT3 is Pro-Apoptotic and Participates in Distinct Basal Apoptotic Pathways.
Cell Cycle 6: 2668-2678.
Warnock L.J., Adamson R., Lynch C.J. and Milner J. (2008)
Crosstalk between site-specific modifications on p53 and histone H3.
Oncogene 27:1639-1644.
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